Follistatin-344 is for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass.

Basic Introduction of Follistatin 344

Basic Introduction of Follistatin 344 Follistatin 344 Chemical: Formula: C121H200N42O39 Molecular weight: 2888.16 Chain: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys Follistatin is also known as activin-binding protein. It is a protein that in humans encoded by…

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