IGF-1LR3 1mg/vial ;
Minimum order quantity : 3vials
GF1 LR3 also known as Long R3 IGF-1 or Insulin-Like Growth Factor-I LR3 is a Human Recombinant, single, non-glycosylated, polypeptide chain containing 83 AA
523 in stock
|Purity:||>99% by HPLC|
|Appearance:||Sterile filtered white lyophilized (freeze-dried) powder|
|AA Sequence:||MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA|
|Reconstitution:||We recommend that this vial be briefly centrifuged prior to opening to settle the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.|
|Storage:||This lyophilized preparation is stable at room temperature when garded from light, but should be kept at -20°C for long term storage, preferably with dessicant. Upon reconstitution, the preparation is stable when stored at 2-8°C. For maximum stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeat freeze/thaw cycles.|
IGF-1 LR3 or LR3-IGF-1,is a synthetic protein and lengthened analogue of humaninsulin-like growth factor 1 (IGF-1).It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence (“arginine 3”), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) (“long”), for a total of 83 amino acids (relative to the 70 of IGF-1). The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1, and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1’s half-life of about 12–15 hours).The amino acid sequence of IGF-1 LR3 is MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA. The products we offer are intended for laboratory research use only.The Products we sold on our store are not been used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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