Ipamorelin is widely known as a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue. It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1. Much like other peptides, ipamorelin stimulates growth hormone release in a similar manner to the growth hormone-releasing hormone (GHRH), which facilitates many of the benefits for which patients seek it out.

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