Modified GRF (1-29) often abbreviated as mod GRF (1-29). Mod-GRF 1-29 is a synthetically made version of growth hormone releasing hormone (GHRH), the chemical in the body responsible for stimulating natural growth hormone production. Sometimes referred to as CJC-1295 without DAC (CJC-1295 w/o dac), it is categorized as a growth hormone secretagogue, a compound which stimulates increased secretion of growth hormone from the pituitary gland. Although similar to Sermorelin, Mod-GRF has four amino acid substitutions made to its chemical structure, hence the alternate name “tetrasubstituted” GRF 1-29. These changes effectively increase the stability of Mod GRF during storage, transportation, and administration while enhancing its affinity for the GHRH receptor. Many scientists have said that the half life of Modified GRF 1-29 and Sermorelin is considered to be way more natural as they are said to produce a short pulse of Human Growth Hormone.

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