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Semax is one of the rare analogues of regulatory peptides which underwent all stages from fundamental investigations to practical usage. According to the research, Semax has a range of neuro-biochemical actions and combines many benefits associated with the use of antidepressants and psychostimulants, such as activation of the brain monoaminergic systems and dopamine synthesis. Semax significantly improves memory and attention in healthy men under extreme conditions of activities. Furthermore, other studies have investigated whether Semax is able to influence learning and memory processes via neurotrophins in rats. It has been demonstrated that this peptide is capable to stimulate operative memory and attention, to increase resistance to hypoxia and to improve brain circulation in experimental animals and human beings over prolonged period (20-24 h after intranasal administration in doses 0.015-0.050 mg/kg).