Adipotide Introduction

Adipotide (FTPP) is a peptidomimetic (a small protein-like chain designed to mimic a peptide), transformed into an experimental proapoptotic drug used for cellular death. Its purpose is to contribute to the weight loss. This substance has shown favorable results in tests and its main feature is its property of rapid loss weight.

Sequence: CKGGRAKDC-GG-D(KLAKLAK)2

Molecular formula: C111H204N36O28S2

Molar Mass: 2555.22 g/mol

Appearance:Sterile filtered white lyophilized (freeze-dried) powder

AA Sequence:CKGGRAKDC-GG-D(KLAKLAK)2

Peptide Sequence

H-Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys-Gly-Gly-Asp-(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2

CID 439302

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to settle the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

Storage: This lyophilized preparation is stable at room temperature when garded from light, but should be kept at -20°C for long term storage, preferably with dessicant. Upon reconstitution, the preparation is stable when stored at 2-8°C. For maximum stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeat freeze/thaw cycles.

More Information:

Adipotide, another name is Fat Targetted Proapoptotic Peptide (FTPP). Clinical Research studies have shown that the peptide-like compound, Adipotide, is able to kill fat cells thereby causing a decrease in the volume and mass of the subcutaneous fat, and this in turn leads to weight loss. Adipotide is able to kill the adipocytes (fat cells) by selectively causing programmed cell death (apoptosis) of the blood vessels supplying the adipocytes.

Adipotide for Fat Loss / Weight Loss:

Adipotide is an experimental treatment that prevents the blood supply to fat cells. This has helped obese monkeys to lose on average 11% of their body weight in four weeks, perhaps opening the way for therapy in humans, according to a recent research study. The study, published in the journal Science Translational Medicine , shows that body mass index and waist circumference of the rhesus monkeys were reduced.

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