Ipamorelin is a peptide agonist of the Ghrelin Hormone Secretagogue Receptor (GHSR), which significantly increases plasma growth hormone (GH) levels in humans. The pharmaceutical company Novo Nordisk originally developed this peptide, but now it has been discontinued because of its low effectiveness. It was tended to be used for the stimulation of growth of children with growth retardation.

Sequence: Aib-His-D-2Nal-D-Phe-Lys
Molecular formula: C38H49N9O5
Molecular Weight: 711.868g/mol
CAS number: 170851-70-4
PubChem CID: 9831659
Ipamorelin Information:
Ipamorelin is a peptide agonist of the Ghrelin Hormone Secretagogue Receptor (GHSR), which significantly increases plasma growth hormone (GH) levels in humans. The pharmaceutical company Novo Nordisk originally developed this peptide, but now it has been discontinued because of its low effectiveness. It was tended to be used for the stimulation of growth of children with growth retardation.
Sequence: Aib-His-D-2Nal-D-Phe-Lys
Molecular formula: C38H49N9O5
Molecular Weight: 711.868g/mol
CAS number: 170851-70-4
PubChem CID: 9831659
How does it work?
Ipamorelin binds of GHSR due to its agonist property to activate it in the search for a biological response. This receptor is located in the hypothalamic ventromedial nucleus of the brain and it is in charge of the production of energy homeostasis (that enhance the regulation of caloric intake by signaling the brain to regulate the sensation of hunger) and the regulation of body weight.
Results and Benefits of Ipamorelin:
Ipamorelin Is Neglected in Research:
Though ipamorelin does not have orphan-drug status at this time, it is still a neglected drug in research settings. Despite promising early studies, interest in ipamorelin has waned following the decision not to pursue it as a treatment for post-operative ileus. Ipamorelin has a number of benefits to offer, not just as a therapeutic, but as a tool for better understanding a number of disease states and their physiologic impacts. Ipamorelin will likely be of interest in research again, once someone jump-starts the field with new data and cutting-edge insight into the benefits of this unique peptide.
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