PT-141 Peptide

PT-141 is a research peptide that carries a half-life of 120 minutes. It has a molecular formula of C50H68N14O10, and it has a molecular weight of 1025.2.

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Molecular formula: C50H68N14O10

Molar Mass: 1025.2

CAS number: 189691-06-3

PubChem: CID 9941379

PT-141 Structural Names: cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10)

PT-141 is a metabolite of Melanotan 2

The PT-141 Structure:


We recommend that this vial be briefly centrifuged prior to opening to settle the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

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What is PT-141?

PT-141 also called Bremelanotide, it is the generic term for a research peptide being studied. Initially, Bremelanotide was conceived as a sunless tanning agent and had its origins from the Melanotan II peptide hormone, which is a synthetic analog of the naturally occurring melanocortin peptide hormone that is used to produce melanogenesis (the production of a pigment found in the skin, eyes, and hair called melanin).

MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning. Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.

Even though there has been an extensive amount of research conducted PT-141 (Bremelanotide), it needs to be emphasized that all of the research that has been conducted with the peptide has been built around scientific studies that have been based on animal test subjects exclusively.  As such, any findings or observations relating to PT-141 (Bremelanotide) should be exclusively contained to a strictly controlled environment such as a medical research facility or a laboratory.


This lyophilized preparation is stable at room temperature when garded from light, but should be kept at -20°C for long term storage, preferably with dessicant. Upon reconstitution, the preparation is stable when stored at 2-8°C. For maximum stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeat freeze/thaw cycles.

PT-141 has also shown potential effects in improving social cognition as well as behaviour, which is also what promotes the peptide as a treatment for a disorder called autism.

Buy PT-141 10mg peptide USA domestic shipping from Giant Lab

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