Difference between MGF and PEG-MGF:
The difference between PEG–MGF and MGF is in the half-life. MGF is responsible for increasing muscle stem cell count through a process called proliferation. Since the task of MGF is to act on neighboring cells from the injection site, the period of its action does not exceed 5-10 minutes. And even at that case the loss of peptide to the blood so fast would still limit the effects of MGF. Therefore, PEG–MGF was created, whose period of exposure was significantly prolonged by pegylation of the mechanical growth factor. PEG molecules can act as a protective coating for the portion of MGF they attract. In theory this would allow MGF to be carried through the bloodstream without being broken down so it can reach its destination more successfully. In conclusion, PEG–MGF can increase the stability, and lifetime of the peptide. Thus, without knowing anything more than multiplication and the law of probability one can see that PEG MGF is significantly more effective.
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Description
PEG-MGF refers to pegylated mechano growth factor, also named PEG IGF-1 Ec. This is a spliced variant of the IGF gene that is used by animals to increase their stem cell count within the muscle tissue while encouraging muscle fibers to mature and fuse. Both PEG-MGF and IGF-1 are polypeptide hormones and are different from myoblasts where embryonic cells develop to muscle fibres. PEG-MGF can cause myoblast division as well as the maturation of the muscle fibres. These functions are necessary for promoting the growth of muscles in adults.
Sequence: PEG-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-rg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH2
Molecular formula: C121H200N42O39
Molecular weight: 2888.16
PubChem SID: 178101669
Synonyms: Pegylated MGF, PEG IGF-1 Ec
The original and natural version of this PEG-MGF peptide is developed where needed and does not travel through the bloodstream; synthetic versions of this chemical have been altered so they may remain stable in the bloodstream for a few minutes. This system is largely used to produce adult muscle as rats mature.
Difference between MGF and PEG-MGF:
The difference between PEG–MGF and MGF is in the half-life. MGF is responsible for increasing muscle stem cell count through a process called proliferation. Since the task of MGF is to act on neighboring cells from the injection site, the period of its action does not exceed 5-10 minutes. And even at that case the loss of peptide to the blood so fast would still limit the effects of MGF. Therefore, PEG–MGF was created, whose period of exposure was significantly prolonged by pegylation of the mechanical growth factor. PEG molecules can act as a protective coating for the portion of MGF they attract. In theory this would allow MGF to be carried through the bloodstream without being broken down so it can reach its destination more successfully. In conclusion, PEG–MGF can increase the stability, and lifetime of the peptide. Thus, without knowing anything more than multiplication and the law of probability one can see that PEG MGF is significantly more effective.
Effects of PEG-MGF Peptide:
Attention for PEG-MGF usage:
When reconstituted, PEG-MGF must be stored at 4°C and away from direct light for 10-14 days. Storage for future use should be done below -18°C. However, you should avoid repeated freeze-thaw cycles.
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